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. 2021 Oct 14;14:720984. doi: 10.3389/fnmol.2021.720984

FIGURE 1.

FIGURE 1

Genetic data about GRIN2A mutations. (A) Pedigrees of the three cases with GRIN2A mutations and their corresponding phenotypes. (B) DNA sequence chromatogram of the GRIN2A mutations. Arrows indicate the positions of the mutations. (C) The amino acid sequence alignment of the three mutations shows that residues K590, K879, and R1067 were highly conserved across vertebrates. JME, juvenile myoclonic epilepsy; JAE, juvenile absence epilepsy; CAE, childhood absence epilepsy; IGE, idiopathic generalized epilepsy.