Table 3.
Relationship between endometrial preparation and pregnancy outcomes in different models.
Pregnancy outcomes | Endometrial preparation | Crude modela | Adjusted modelb | ||
---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | ||
Positive pregnancy | NC | Reference | Reference | ||
mNC | 0.68 (0.51–0.91) | 0.008 | 0.76 (0.56–1.03) | 0.077 | |
Clinical pregnancy | NC | Reference | Reference | ||
mNC | 0.60 (0.44–0.82) | 0.001 | 0.66 (0.48–0.92) | 0.014 | |
Live birth | NC | Reference | Reference | ||
mNC | 0.63 (0.46–0.85) | 0.003 | 0.71 (0.51–0.98) | 0.039 |
BMI, body mass index; FSH, follicle stimulating hormone; OR, odds ratio; CI, confidence interval; mNC, modified natural cycle; NC, natural cycle; FET, frozen-thawed embryo transfer.
No adjustments for other covariates.
Adjusted for female age (<37 years, ≥37 years), infertility duration, gravidity, parity, infertility type (primary, secondary), BMI (<25, ≥25 kg/m2), basic FSH (<10, ≥10 UI/L), initial treatment (IVF, ICSI), number of oocytes retrieved (≤ 3, 4–9, 10–15, >15), total number of embryos (<3, ≥3), number of transferred embryos, protocol in fresh cycle (fresh embryo transfer, freeze-all strategy), good-quality embryos (yes, no) and endometrial thickness before FET.
P < 0.05 indicated statistically significant differences between groups.