Table 2.

DAMs between CLas-infected and healthy leaves.

No.	Metabolites	VIPa	P-valueb	Log2FoldChangec	KEGG compound id
1	Rutin	1.38	2.12E-02	2.73	C05625
2	Xanthurenic acid	1.04	2.43E-05	2.23	C02470
3	D-Mannitol	1.55	2.52E-07	2.10	C00392
4	Scopoletin	1.28	2.04E-02	1.70	C01752
5	4-Hydroxybenzoate	1.51	1.14E-06	1.70	C00156
6	Dopamine	1.54	5.34E-08	1.68	C03758
7	Vanillin	1.54	4.74E-05	1.59	C00755
8	4-Hydroxyphenylpyruvate	1.34	1.42E-02	1.40	C01179
9	D-Proline	1.43	2.44E-06	1.37	C00763
10	Glycitein	1.34	3.65E-03	1.19	C14536
11	L-Proline	1.50	1.88E-06	1.17	C00148
12	Phloretin	1.53	8.91E-06	1.13	C00774
13	Gentisic acid	1.48	1.76E-05	1.09	C00628
14	Maleic acid	1.47	6.97E-06	1.07	C01384
15	Vanillic acid	1.34	3.79E-03	1.06	C06672
16	Apigenin	1.30	1.87E-03	0.96	C01477
17	L-Glutamine	1.39	9.50E-05	0.89	C00064
18	LysoPC(16:0)	1.41	8.80E-05	0.85	C04230
19	Mevalonic acid	1.42	4.74E-05	0.83	C00418
20	5,10-methylene-THF	1.32	5.97E-04	0.82	C00143
21	L-Carnitine	1.42	2.01E-05	0.82	C00318
22	Guanosine	1.35	7.43E-04	0.79	C00387
23	N-Acetylmannosamine	1.12	1.42E-02	0.72	C00645
24	Phenol	1.26	2.70E-03	0.70	C00146
25	5'-Deoxyadenosine	1.01	2.30E-02	0.66	C05198
26	D-(+)-Galactose	1.33	2.36E-04	0.65	C00984
27	Gamma-Butyrolactone	1.17	4.82E-03	0.64	C01770
28	Homocitrate	1.28	1.31E-03	0.61	C01251
29	Capecitabine	1.18	7.14E-03	0.60	C12650
30	Synephrine	1.28	1.08E-03	0.57	C04548
31	Oleoyl-CoA	1.32	8.79E-04	0.53	C00510
32	Isomaltose	1.25	2.51E-03	0.51	C00252
33	D-Maltose	1.21	1.60E-02	0.49	C00208
34	L-Pyroglutamic acid	1.08	1.12E-02	0.49	C01879
35	Thiamine	1.41	1.26E-04	0.47	C00378
36	D-Mannose	1.03	2.39E-02	0.41	C00159
37	1,2,3-Trihydroxybenzene	1.14	8.66E-03	0.40	C01108
38	Sucrose	1.14	7.63E-03	0.37	C00089
39	3-Methylindole	1.28	2.13E-03	0.35	C08313
40	2-Ethoxyethanol	1.33	1.20E-03	0.30	C14687
41	Adenosine	1.06	1.96E-02	0.28	C00212
42	O-Phosphoethanolamine	1.19	7.30E-03	0.21	C00346
43	cis-9-Palmitoleic acid	1.21	2.47E-03	−0.28	C08362
44	Indoleacetic acid	1.09	1.32E-02	−0.34	C00954
45	Aminocaproic acid	1.16	7.61E-03	−0.43	C02378
46	L-Malic acid	1.03	1.88E-02	−0.47	C00149
47	beta-Hydroxybutyrate	1.24	1.08E-02	−0.48	C01089
48	2'-Deoxy-D-ribose	1.22	5.57E-03	−0.49	C01801
49	4-Hydroxycinnamic acid	1.25	2.17E-03	−0.49	C00811
50	PA(16:0/18:1(9Z))	1.21	3.41E-03	−0.51	C00416
51	Curcumin	1.55	5.09E-07	−0.59	C10443
52	1-Deoxy-D-xylulose 5-phosphate	1.24	2.85E-03	−0.59	C11437
53	Stearic acid	1.40	8.21E-05	−0.59	C01530
54	N-Acetyl-L-glutamate	1.07	1.13E-02	−0.59	C00624
55	trans-Vaccenic acid	1.21	5.53E-03	−0.65	C08367
56	Gamma-Glutamylcysteine	1.32	9.07E-04	−0.66	C00669
57	Phenylacetylglycine	1.02	3.83E-02	−0.66	C05598
58	L-Citrulline	1.18	9.17E-03	−0.73	C00327
59	Nicotinamide	1.05	1.26E-02	−0.74	C00153
60	4-Pyridoxic acid	1.22	3.15E-03	−0.76	C00847
61	Cyclohexylamine	1.29	1.10E-02	−0.80	C00571
62	Glycerophosphocholine	1.09	2.69E-02	−0.80	C00670
63	Pantothenate	1.33	2.77E-04	−0.84	C00864
64	L-Pipecolic acid	1.22	3.41E-02	−0.94	C00408
65	Prunasin	1.41	1.32E-03	−1.24	C00844
66	Isorhamnetin	1.42	4.78E-03	−1.29	C10084
67	D-Tagatose	1.43	1.38E-05	−1.35	C00795
68	17-beta-Estradiol-3-glucuronide	1.47	4.07E-04	−1.38	C05503
69	Dihydroxyacetone	1.44	1.05E-05	−1.60	C00184
70	Inosine	1.52	3.28E-07	−1.67	C00294
71	Raffinose	1.53	1.14E-04	−1.73	C00492

^aVIP: importance of the variable projection of substance in the OPLS-DA model.

^bP-value: the P value of substance in the t-test of the group.

^cLog2FoldChange: logarithm of the fold change of DAMs between CLas-infected and healthy leaves to base 2.