Table 2.
Results of heterogeneity estimation and publication bias assessment, and meta-analysis for the risk of cancer among men with infertility compared to men without infertility.
| Outcome | Sample size | Publication bias test | Heterogeneity(I2%)* | Pooled overall OR (95% CI)* | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Men with infertility | Men without infertility | Harbord test | Egger test | Begg test | ||||||
| Total population | Number of events | Total population | Number of events | |||||||
| Composite all cancers | 168327 | 1551 | 2252806 | 12164 | 0.365 | 0.188 | 0.697 | 77.1% | 1.43 (1.25-1.64) | |
| Individual cancers | ||||||||||
| Prostate cancer | 138699 | 324 | 1951019 | 3875 | 0.348 | 0.392 | 1.000 | 79.9% | 1.48 (1.05-2.08) | |
| Testicular cancer | 130242 | 183 | 1095820 | 849 | 0.497 | 0.152 | 0.497 | 30.4% | 1.91 (1.52-2.42) | |
| Melanoma cancer | 96516 | 121 | 781263 | 540 | Insufficient data | Insufficient data | 0.317 | 0.0% | 1.31 (1.06-1.62) | |
*Bold values indicate statistical significance.