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. 2021 Oct 14;8:745360. doi: 10.3389/fmolb.2021.745360

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Copyright © 2021 Pietri, Tontini, Brogioni, Oldrini, Robakiewicz, Henriques, Calloni, Abramova, Santini, Malić, Miklić, Lisnic, Bertuzzi, Unione, Balducci, de Ruyck, Romano, Jimenez-Barbero, Bouckaert, Jonjic, Rovis and Adamo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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STD-NMR (D₂O, 600 MHz) of a DP7 fragment in complex with MenX0.1 mAb. (A) ¹H NMR of the oligosaccharide in the presence of MenX0.1 mAb (50:1 M ratio). (B) STD NMR spectrum obtained for the complex upon on-resonance irradiation at 7 ppm; (C) STD-NMR spectrum obtained for the complex upon on-resonance irradiation at 8 ppm. All sugar ring protons display transfer of saturation, with higher relative intensities for positions H-1 and H-4.