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. 2021 Oct 14;12:751380. doi: 10.3389/fphar.2021.751380

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Copyright © 2021 Zou, Li and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative M-mode echocardiograms obtained with two-dimensional guidance from a long-axis ventricular view in each group (A) and effects of CRS2 and DMB treatment on echocardiographic variables including percent left ventricular ischemic area (LVIA%) (B), LV ejection fraction (LVEF) (C), LV fractional shortening (LVFS) (D), LV volumes at end cardiac systole (LVESV) (E) and LV volumes at end cardiac diastole (LVEDV) (F). Data are expressed as mean ± SE (n = 8–10 for each group). *p < 0.05 vs SHAM + SHAM + VEH at each time point; ¥ p < 0.05 vs week 6; §p < 0.05, MI + STNx + DMB vs MI + STNx + VEH.