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Effects of CRS2 and DMB treatment on renal function assessed by serum creatinine concentrations (A), urinary kidney injury molecule-1 (Kim-1) (B), creatinine clearance (C) and proteinuria (D). Data are expressed as mean ± SE (n = 8–10 for each group). *p < 0.05 vs SHAM + SHAM + VEH at each time point; ¥ p < 0.05 vs week 6; §p < 0.05, MI + STNx + DMB vs MI + STNx + VEH.
