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. 2021 Sep 27;29(6):582–595. doi: 10.4062/biomolther.2021.125

Table 3.

Biomarker candidates and pathway analyses in studies included in systematic review of IBD

Author (year) Cohort IBD type Sample Biomarker candidate Pathway analysis
Manfredi et al. (2019) Italy CD Serum Fatty acid
PUFA
No
Iwatani et al. (2020) Japan CD Plasma PS No
Horta et al. (2021) Spain Fatigue CD Plasma PC
LPC
PE
PI
PS
SM
Eicosanoid
Yes
Guan et al. (2020) China CD/UC Plasma FA
GP
SL
Prenol lipid
Sterol lipid
Yes
Daniluk et al. (2019) Poland CD Serum GP
Cer
Yes
Diab et al. (2019) Norway UC Tissue PC
SM
Cer
No
Fan et al. (2015) Australia CD Plasma PC
Ether PC
Ether PE
LPE
PS
Cer
No
UC
Bazarganipour et al. (2019) Germany UC Plasma Fatty acid
LPC
SM
Cer
TG
Eicosanoid
No
Tissue
Jansson et al. (2009) Sweden CCD Feces FA Yes
Murgia et al. (2018) Italy CD Plasma Fatty acid
PC
LPC
PS
TG
No
Ehehalt et al. (2004) Germany CD Tissue PC
LPC
No
Bene et al. (2006) Hungary UC Plasma AcylCar No
Pearl et al. (2014) UK UC Tissue Eicosanoid No
Braun et al. (2009) Germany CD Tissue PC
LPC
SM
No
Scoville et al. (2018) US CD Serum FA Yes
Tefas et al. (2020) Romania CD Serum FA
PC
LPC
SM
DG
Yes
Masoodi et al. (2013) UK UC Tissue Eicosanoid No
Sewell et al. (2012) UK CD Tissue, Cell PI
PC
No
Lai et al. (2019) US Active CD Serum Fatty acid
Acylcarnitine
Yes