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. 2021 Oct 14;15:718958. doi: 10.3389/fnins.2021.718958

TABLE 2.

Results of analysis of covariance to assess effects of possible confounds age, scanner site, gender and global metrics.

Source df1, df2 F p Effect size
Grey matter volume
Participant group (A) 1, 43 4.87 0.033 0.10
ROI (B) 4.22, 181.56 3.63 0.006 0.08
Scanner site (C) 2, 43 0.61 0.549 0.03
Age (D) 1, 43 1.10 0.299 0.03
Gender (E) 1, 43 0.30 0.587 0.01
Global volume (F) 1, 43 0.95 0.335 0.02
A × B 4.22, 181.56 4.85 0.001 0.10
A × C 2, 43 0.02 0.976 0.00
A × E 1, 43 0.00 0.963 0.00
A × B × C 8.44, 181.56 0.39 0.934 0.02
A × B × E 4.22, 181.56 0.86 0.492 0.02
A × C × E 2, 43 0.08 0.920 0.00
A × B × C × E 8.44, 181.56 0.30 0.968 0.01
B × C 8.44, 181.56 1.19 0.308 0.05
B × D 4.22, 181.56 2.14 0.074 0.05
B × E 4.22, 181.56 0.53 0.723 0.01
B × F 4.22, 181.56 0.48 0.764 0.01
B × C × E 8.44, 181.56 2.64 0.008 0.11
C × E 2, 43 0.77 0.471 0.03
Cortical thickness
Participant group (A) 1, 43 0.00 0.962 0.00
ROI (B) 11.00, 473.00 1.11 0.352 0.03
Scanner site (C) 2, 43 0.86 0.432 0.04
Age (D) 1, 43 0.03 0.861 0.00
Gender (E) 1, 43 0.20 0.658 0.01
Global thickness (F) 1, 43 0.51 0.478 0.01
A × B 11.00, 473.00 1.55 0.112 0.04
A × C 2, 43 0.66 0.522 0.03
A × E 1, 43 0.00 0.948 0.00
A × B × C 22.00, 473.00 0.85 0.666 0.04
A × B × E 11.00, 473.00 0.61 0.823 0.01
A × C × E 2, 43 2.94 0.064 0.12
A × B × C × E 22.00, 473.00 0.68 0.862 0.03
B × C 22.00, 473.00 0.79 0.746 0.04
B × D 11.00, 473.00 0.65 0.783 0.02
B × E 11.00, 473.00 0.54 0.875 0.01
B × F 11.00, 473.00 0.86 0.582 0.02
B × C × E 22.00, 473.00 0.50 0.975 0.02
C × E 2, 43 3.68 0.033 0.15
Cortical surface area
Participant group (A) 1, 43 7.52 0.009 0.15
ROI (B) 2.26, 97.28 2.72 0.064 0.06
Scanner site (C) 2, 43 0.34 0.712 0.02
Age (D) 1, 43 1.79 0.188 0.04
Gender (E) 1, 43 0.20 0.656 0.01
Global surface area (F) 1, 43 0.71 0.403 0.02
A × B 2.26, 97.28 6.62 0.001 0.13
A × C 2, 43 0.03 0.968 0.00
A × E 1, 43 0.10 0.749 0.00
A × B × C 4.53, 97.28 0.10 0.989 0.01
A × B × E 2.26, 97.28 0.81 0.459 0.02
A × C × E 2, 43 0.62 0.542 0.03
A × B × C × E 4.53, 97.28 0.46 0.788 0.02
B × C 4.53, 97.28 0.71 0.601 0.03
B × D 2.26, 97.28 2.89 0.054 0.06
B × E 2.26, 97.28 0.05 0.967 0.00
B × F 2.26, 97.28 0.61 0.565 0.01
B × C × E 4.53, 97.28 2.35 0.052 0.10
C × E 2, 43 0.27 0.765 0.01

Effect size shown is partial eta-squared. Huynh-Feldt correction applied to correct for violation of sphericity. Significance is illustrated by boldface.