Table 1.
Baseline characteristics according to ASCVD stratification
| VHR | Non-VHR | P for trend | |||
|---|---|---|---|---|---|
| N | Total 2542 | VHR-1 779 | VHR-2 1763 | 7402 | |
| Male,%(n) | 85% (2157) | 87% (680) | 84% (1477) | 69% (5111) | <0.001 |
| Hypertension,%(n) | 71% (1799) | 63% (494) | 74% (1305) | 63% (4630) | <0.001 |
| Borderline blood pressure,%(n) | 14% (355) | 16% (128) | 13% (227) | 22% (1633) | <0.001 |
| DM,%(n) | 41% (1048) | 37% (286) | 43% (762) | 30% (2254) | <0.001 |
| Pre-DM,%(n) | 41% (1047) | 44% (340) | 40% (707) | 47% (3472) | <0.001 |
| Obesity,%(n) | 12% (300) | 9% (73) | 13% (227) | 9% (688) | <0.001 |
| Overweight,%(n) | 51% (1299) | 52% (405) | 51% (894) | 50% (3723) | <0.001 |
| Low HDL-C,%(n) | 55% (1388) | 57% (446) | 53% (942) | 42% (3141) | <0.001 |
| Borderline HDL-C,%(n) | 39% (989) | 36% (284) | 40% (705) | 47% (3478) | <0.001 |
| Current smoking,%(n) | 50% (1278) | 46% (358) | 52% (920) | 33% (2452) | <0.001 |
| Former smoker,%(n) | 20% (520) | 23% (178) | 19% (342) | 17% (1293) | <0.001 |
| Family history of CAD,%(n) | 31% (790) | 31% (244) | 31% (546) | 32% (2380) | 0.315 |
| Length of hospitalization(days) | 4(3-7) | 5(3-7) | 4(3-6) | 4(3-5) | <0.001 |
| Age(years) | 58(48-65) | 57(50-64) | 58(47-66) | 59(52-65) | <0.001 |
| BMI(kg/m2) | 26.0(24.2-28.1) | 26.0(24.2-28.1) | 26.0(24.2-28.3) | 25.7(23.7-27.7) | <0.001 |
| TG(mmol/L) | 1.5(1.1-2.2) | 1.5(1.1-2.1) | 1.5(1.1-2.2) | 1.5(1.1-2.1) | 0.046 |
| TC(mmol/L) | 3.9(3.3-4.6) | 3.9(3.2-4.6) | 3.9(3.3-4.6) | 4.0(3.3-4.7) | <0.001 |
| LDL-C(mmol/L) | 2.3(1.8-2.9) | 2.3(1.8-2.9) | 2.3(1.8-2.9) | 2.4(1.8-3.0) | 0.006 |
| HDL-C(mmol/L) | 1.0(0.8-1.2) | 0.9(0.8-1.2) | 1.0(0.8-1.2) | 1.0(0.9-1.3) | <0.001 |
| ApoAI (g/L) | 1.3(1.1-1.4) | 1.2(1.1-1.4) | 1.3(1.1-1.5) | 1.3(1.2-1.5) | <0.001 |
| ApoB(g/L) | 0.8(0.7-1.1) | 0.8(0.7-1.1) | 0.8(0.7-1.0) | 0.8(0.7-1.0) | 0.654 |
Data shown are %(n) or median (inter-quartile range). P values are shown for trend of “VHR-1 vs. VHR-2 vs. Non-VHR”. ASCVD, atherosclerotic cardiovascular disease; VHR, very-high-risk; VHR-1, subgroup of VHR with ≥2 major ASCVD events; VHR-2, subgroup of VHR with 1 major ASCVD events and ≥2 high-risk conditions; DM, diabetes; HDL-C, high-density lipoprotein cholesterol; CAD, coronary artery disease; BMI, body mass index; TG, triglycerides; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; Apo, apolipoprotein.