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Kinetic binding constants for Ab:antigen interaction determined by BLI.
| Antibody | Antigen | pH | Average KD app (pM)a |
|---|---|---|---|
| MR72 | EBOV GPCL | 5.5 | 2±1 |
| MR72~NPC2 | EBOV GPCL | 5.5 | 3±4 |
| MR72~IGF2 | EBOV GPCL | 5.5 | 2±2 |
| 548 | Human NPC1-C | 5.5 | 7±10 |
| 548~NPC2 | Human NPC1-C | 5.5 | <1 |
| 548~IGF2 | Human NPC1-C | 5.5 | <1 |
(a)KD app, apparent equilibrium dissociation constant. Mean±SD determined from three independent experiments
