Table 23.

Aza-Michael addition of primary amines to β-trifluromethyl-β-phenylnitroolefin catalyzed nitrogen heterocyclic carbene.

103	R1	Yield [%]	ee [%]
a	C6H5CH2-	90	91
b	2-MeC6H4CH2-	67	91
c	4-MeOC6H4CH2-	89	92
d	3,5-(MeO)2C6H3CH2-	56	86
e	C6H5(CH2)2-	85	86
f	4-BrC6H4(CH2)2-	68	87
g	CH3(CH2)2-	80	92
h	C7H15CH2-	87	95
i	C6H5(CH2)3-	82	93
j	(CH3)2CH(CH2)2-	79	89
k	cyclopropyl-	79	97
l	cyclobutyl-	78	94
m	2-pyridylethyl-	87	93
n	BocHN(CH2)2	79	91
o	MeO(CH2)3-	87	87
p	(Me)2N(CH2)2-	99	91
q	2-thienyl(CH2)2-	98	93