Table 4.

Asymmetric aza-Michael addition of 4-nitrophthalimide to α,β-unsaturated ketones.

20	R1	R2	Yield [%]	ee [%]
a	Ph	Ph	55	>99
b	2-Cl-C6H4	Ph	61	95
c	3-Cl-C6H4	Ph	65	98 (s)
d	4-Cl-C6H4	Ph	56	99
e	4-F-C6H4	Ph	60	>99
f	4-Br-C6H4	Ph	62	99
g	4-Me-C6H4	Ph	69	99
h	4-NO2-C6H4	Ph	49	>99
i	Ph	4-Cl-C6H4	54	99
j	4-F-C6H4	4-F-C6H4	71	99
k	iPr	Me	75	97
l	n-Pr	Me	88	96
m	n-Bu	Me	89	95
n	n-Pen	Me	98	95
o	n-Hex	Me	90	96
p	Me	Et	51	95