Table 2.
Baseline characteristics and risk stratification of the HEART Score of patients with or without MACE and performance of the individual components of the HEART Score in the derivation cohort
| No MACE | MACE (%) | Total | |
| Baseline | |||
| Age, years mean (SD) | 65.6 (13.6) | 68.8 (12.0) | 65.9 (13.5) |
| Male sex (%) | 546 (50.6) | 87 (75.0) | 633 (53.0) |
| HR, bpm (SD) | 92 (19) | 91 (20) | 92 (20) |
| Systolic BP, mm Hg (SD) | 154 (29) | 156 (30) | 154 (30) |
| Diastolic BP, mm Hg (SD) | 89 (19) | 91 (23) | 89 (19) |
| Event-time-to-troponin, hours (SD) | 14 (2) | 17 (4) | 14 (2) |
| HEART Score median (IQR) | 4 (3) | 7 (3) | 5 (3) |
| Risk category | |||
| HEART 0–3 pts | 315 (98.4%) | 5 (1.6%) | 320 (26.5%) |
| HEART 4–6 pts | 648 (92.7%) | 51 (7.3%) | 699 (57.9%) |
| HEART 7–10 pts | 122 (64.6%) | 67 (35.4%) | 189 (15.6%) |
| Performance | AUC | 95% CIs | P value |
| HEART Score | 0.814 | 0.78 to 0.85 | 0.00 |
| Components | |||
| History | 0.693 | 0.65 to 0.74 | 0.00 |
| ECG findings | 0.686 | 0.63 to 0.74 | 0.00 |
| Age | 0.560 | 0.51 to 0.61 | 0.03 |
| Risk factors | 0.551 | 0.50 to 0.60 | 0.06 |
| Troponin | 0.714 | 0.66 to 0.77 | 0.00 |
AUC, area under the receiver operating characteristic curve; BP, blood pressure; HEART, history, ECG, age, risk factors and troponin; HR, heart rate; MACE, major adverse cardiac event.;