TABLE 1.
Baseline characteristics of GEP‐NET patients without prior diabetes mellitus
| Variable | No SSA treatment N = 4451 | Received SSA treatment N = 784 | P‐value | |
|---|---|---|---|---|
| N (column %) | ||||
| Age | 65–69 | 1739 (39.1%) | 340 (43.4%) | .0002 |
| 70‐74 | 1026 (23.1%) | 201 (25.6%) | ||
| 75‐79 | 765 (17.2%) | 133 (17.0%) | ||
| 80+ | 921 (20.7%) | 110 (14.0%) | ||
| Gender | Male | 2210 (49.7%) | 378 (48.2%) | .46 |
| Race/ethnicity | Non‐Hispanic white | 3365 (75.6%) | 673 (85.8%) | <.0001 |
| Non‐Hispanic black | 493 (11.1%) | 59 (7.5%) | ||
| Hispanic | 248 (5.6%) | 32 (4.1%) | ||
| Asian/Pacific Islander | 268 (6.0%) | 18 (2.3%) | ||
| Tumor size | <1 cm | 796 (17.9%) | 20 (2.6%) | <.0001 |
| 1‐2 cm | 837 (18.8%) | 159 (20.3%) | ||
| >2 cm | 1334 (30.0%) | 373 (47.6%) | ||
| Unknown | 1484 (33.3%) | 232 (29.6%) | ||
| Stage | I | 1905 (46.4%) | 53 (7.1%) | <.0001 |
| II | 416 (10.1%) | 60 (8.0%) | ||
| III | 676 (16.5%) | 136 (18.2%) | ||
| IV | 1108 (27%) | 498 (66.7%) | ||
| Histological grade | Well differentiated | 1099 (24.7%) | 237 (62.5%) | <.0001 |
| Moderately differentiated | 311 (7.0%) | 95 (25.1%) | ||
| Poorly differentiated and undifferentiated | 626 (14.1%) | 47 (12.4%) | ||
| Unknown | 2415 (54.3%) | 405 (51.7%) | ||
| Primary site | Appendix | 212 (4.8%) | 12 (1.5%) | <.0001 |
| Colon | 704 (15.8%) | 71 (15.4%) | ||
| Pancreas | 719 (16.2%) | 193 (24.6%) | ||
| Rectum | 929 (20.1%) | 27 (3.4%) | ||
| Stomach | 470 (10.6%) | 35 (4.5%) | ||
| Small intestine | 1417 (31.2%) | 446 (56.9%) | ||
| Prior pancreatic surgery | 257 (5.8%) | 46 (5.9%) | .92 | |
| Carcinoid syndrome | 618 (13.9%) | 359 (45.8%) | <.0001 | |
| Prior chemotherapy | 430 (9.7%) | 395 (50.4%) | <.0001 | |
| Prior radiotherapy | 233 (5.2%) | 85 (10.8%) | <.0001 | |
| Modified Charlson comorbidity index | 0 | 2457 (55.2%) | 553 (70.5%) | <.0001 |
| 1–2 | 1021 (22.9%) | 138 (17.6%) | ||
| >3 | 210 (4.7%) | 13 (1.67%) | ||
| Unknown | 763 (17.1%) | 80 (10.2%) | ||
| Developed diabetes mellitus | 1079 (24.2%) | 240 (30.6%) | .0002 |