TABLE 3.
Summary of polymorphisms identified in the TK gene corresponding to amino acid sequence between residues 122 and 232
Virus type | Nucleotide substitution | Amino acid changea | Reference |
---|---|---|---|
HSV-1 | C513T (TGC→TGT) | −(residue 171) | This study |
A528G (CGA→CGG) | −(residue 176) | 15 | |
C575T (GCC→GTC) | Ala→Val (residue 192) | This study | |
C672T (GGC→GGT) | −(residue 224) | 18 | |
HSV-2 | G420T (TTG→TTT) | Leu→Phe (residue 139) | This study |
−, deletion.