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. 2021 Oct 14;12:759170. doi: 10.3389/fmicb.2021.759170

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Copyright © 2021 Yong, Zhou, Liu, Liu, Wu and Fang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic profile analysis of Apramycin-resistant and sensitive Salmonella. (A) PLS-DA score of Apramycin-resistant and sensitive Salmonella in negative ESI modes. (B) PLS-DA score of Apramycin-resistant and sensitive Salmonella in positive ESI modes. (C) Cluster analysis of different metabolites in negative ESI modes. (D) Cluster analysis of different metabolites in positive ESI modes. (E) Volcano map of the metabolites of Apramycin-resistant Salmonella in negative ESI modes. (F) Volcano map of the metabolites of Apramycin-resistant Salmonella in positive ESI modes. “A” represents Apramycin-induced resistant Salmonella ATCC13312 and “S” represents Apramycin-sensitive Salmonella ATCC13312.