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. 2021 Oct 14;12:759170. doi: 10.3389/fmicb.2021.759170

Figure 3.

Figure 3

Effect of exogenous citrulline and glutamine on intracellular drugs, NADH, and proton-motive force (PMF). (A) Concentration of Apramycin in bacteria cultured with different exogenous substances. (B) The NADH content of bacteria cultured with different exogenous substances. (C) The PMF of Apramycin-resistant Salmonella cultured with citrulline and (or) glutamine. (D) Survival curve of bacteria in different media with or without CCCP. “Apr” represents Apramycin alone, “Apr+Cit” represents the combination of Apramycin and citrulline; “Apr+Gln” represents the combination of Apramycin and glutamine; “Apr+Cit+Gln” represents the combination of Apramycin, citrulline, and glutamine; “K” represents the control group; “Cit” represents citrulline alone; “Gln” represents glutamine alone; and “Cit+Gln” represents citrulline plus glutamine. Results are displayed as the mean±SEM, and significant differences are identified (*p <0.05; **p <0.01, compared with the group without any exogenous substances) as determined using SPSS Statistics 26.0. Three biological repeats were carried out.