Table 1.
Significant laboratory tests at admission in our center.
| Results | Reference range | |
|---|---|---|
| Hemoglobin | 9.2 g/dl | 11.5–16.5 |
| Lactic dehydrogenase | 983 U/L | 84–480 |
| Haptoglobin | <2 mg/dl | 15–160 |
| Total lymphocyte count | 7,150/mmc | 3,600–9,800 |
| Lymphocyte subsets | ||
| CD3+TCRαβ+CD4−CD8− DNT cells | 5.1% (365/mmc) | <1.5% of total lymphocytes |
| B cells CD 19+ | 2.6% (186/mmc) | 6–19% |
| B cells CD27+ (CD19+ tot) | 15.9% (1,137/mmc) | >15% |
| CD3CD25+/CD3HLADR+ ratio | 0% | >1 |
| CD3+TCR αβ+ CD4−CD8− B220+ cells a | 82.7% (5,913/mmc) | <60% |
| Autoimmune lymphoproliferative syndrome (ALPS) biomarkers | ||
| Plasma sFASL levels | 0.5 pg/ml | 0 >200 in ALPS |
| Elevated plasma interleukin-10 levels | <1 pg/ml | <1 pg/ml >20 in ALPS |
| Elevated serum or plasma vitamin B12 levels | 374 ng/L | 191–663 >1,500 in ALPS |
| Elevated plasma interleukin-18 levels | 5,750 pg/ml | 36–258 >500 in ALPS |
| Immunoglobulin G | 254 mg/dl | 700–1600 |
| Immunoglobulin A | 13 mg/dl | 70–400 |
| Immunoglobulin M | 299 mg/dl | 40–230 |