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. 2021 Oct 14;12:733225. doi: 10.3389/fimmu.2021.733225

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Copyright © 2021 Dong, Ye, Zhao, Wang, Zhang, Wang, Zou, Wang, Yao, Chen, Zhou, Zhang and Luo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of alteration in biomarker levels in the first and second trimester. (A) Serum levels of L-palmitoylcarnitine in the first trimester(P=0.040); (B) serum levels of glycocholic acid in the first trimester (P=0.000); (C) serum levels of ACOX1 in the first trimester (P=0.022); (D) Serum levels of L-palmitoylcarnitine in the second trimester(P=0.012); (E) serum levels of glycocholic acid in the second trimester (P=0.000); (F) serum levels of ACOX1 in the second trimester (P=0.000). (*P < 0.05; **P < 0.01).