Table 1.
Clinical characteristics and perinatal outcomes of pregnant women with ICP and healthy pregnant controls.
| Variable | ICP (mean±SD) | Control (mean±SD) | P-value |
|---|---|---|---|
| Placental samples (n) | 10 | 10 | / |
| Serum samples (n) | 40 | 40 | / |
| Maternal age (years) | 28.8 ± 5.3 | 27.9 ± 3.0 | 0.272 |
|
Gestational weeks
(Blood collection) |
36.9 ± 1.9 | 36.3 ± 0.4 | 0.064 |
| TBA (μmol/L) | 32.4 ± 18.0 | 3.5 ± 1.8 | 0.000 |
| ALT (IU/L) | 80.6 ± 114.2 | 10.9 ± 5.8 | 0.000 |
| AST (IU/L) | 66.5 ± 82.7 | 18.1 ± 14.0 | 0.001 |
|
Gestational weeks
(Delivery) |
38.6 ± 1.8 | 39.7 ± 0.6 | 0.000 |
| Newborn weight (g) | 3176.9 ± 648.5 | 3348.3 ± 503.2 | 0.295 |
TBA, total bile acid; ALT, alanine transaminase; AST, aspartate transaminase. Statistical analyses were performed using the t-test; *P < 0.05 was considered to reflect significance.