Table 3.
Pathway analysis of metabolite changes in ICP in the placenta.
| Pathway Name | Total | P-value |
|---|---|---|
| Fatty acid metabolism | 50 | 2.51E-02 |
| Primary bile acid biosynthesis | 47 | 4.06E-02 |
| Inositol phosphate metabolism | 39 | 1.29E-01 |
| Ascorbate and aldarate metabolism | 45 | 8.92E-02 |
| tyrosine metabolism | 76 | 2.02E-01 |
| Starch and sucrose metabolism | 50 | 4.29E-01 |
| Pentose and glucuronate interconversions | 53 | 4.44E-01 |
| Aminoacyl-tRNA biosynthesis | 75 | 6.78E-01 |
| Arginine and proline metabolism | 77 | 5.74E-01 |
| Tryptophan metabolism | 79 | 3.79E-01 |
| Amino sugar and nucleotide sugar metabolism | 88 | 5.61E-01 |
The analysis was conducted by the module of enrichment analysis of MetaboAnalyst 4.0. *P<0.05 was considered to reflect significance. The key metabolic pathway are bolded.