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. 2021 Aug 26;2(10):100221. doi: 10.1016/j.jtocrr.2021.100221

Table 5.

Proposed Scales for Intraoperative Quantification of Surgical Complexity in Early NSCLC After Neoadjuvant Immunotherapy

Grade Characteristics
Nonmalignant lymphadenopathy
0 Lymphadenopathy <1 cm
1 Lymphadenopathy 1 to <2 cm
2 Lymphadenopathy 2 to <3 cm
3 Lymphadenopathy ≥3 cm
Peripheral (pleural) fibrosis
1 Mild fibrosis (no substantial impact on conduct of surgical resection)
2 Moderate fibrosis (requires increased effort and dissection during resection but otherwise does not severely impact the conduct of the surgery)
3 Severe fibrosis (substantially impacts the conduct of the operation by increasing the duration of or blood loss during the surgery, or requires converting minimally invasive to open surgery)
4 Severe fibrosis resulting in unresectability
Central vs. peripheral lung cancer
1 Central (inner two-thirds of lung)
2 Peripheral (outer two-thirds of lung)
Perihilar/lobar or mediastinal adhesions
1 Mild fibrosis (no substantial impact on conduct of surgical resection)
2 Moderate fibrosis (requires increased effort and dissection during resection but otherwise does not severely impact the conduct of the surgery)
3 Severe fibrosis (substantially impacts the conduct of the operation by increasing the duration of or blood loss during the surgery, or requires converting minimally invasive to open surgery)
4 Severe fibrosis resulting in unresectability