Table 1. Subtype distribution of microbial CRISPRs and identified IHF binding sties.
15,274 CRISPR loci were identified in bacterial and archaeal genomes. Closely related microbial genomes, which causes an over-representation of certain CRISPR subtypes (I-B, I-C, I-E, I-F, II-A, II-C, III-A) (“Redundant” column), were systematically removed (“Non-Redundant” columns). The number of non-redundant CRISPR leaders in containing at least one, or at least two unique IHF binding sites is reported. See also Figure S1.
| Number of leaders |
|||||
|---|---|---|---|---|---|
| Redundant | Non-Redundant | ||||
|
|
|||||
| Subtype | All | All | One or more IHF sites | Two or more IHF sites | |
| Type I | I-A | 296 | 187 | 27 | 3 |
| I-B | 1516 | 761 | 238 | 36 | |
| I-C | 1324 | 754 | 178 | 24 | |
| I-D | 152 | 117 | 14 | 2 | |
| I-E | 5068 | 1329 | 335 | 84 | |
| I-F | 1683 | 536 | 444 | 279 | |
| I-U | 157 | 109 | 5 | 0 | |
| I-V | 2 | 2 | 0 | 0 | |
| Type II | II-A | 823 | 178 | 39 | 4 |
| II-B | 34 | 9 | 5 | 0 | |
| II-C | 662 | 337 | 103 | 17 | |
| Type III | III-A | 853 | 242 | 93 | 11 |
| III-B | 409 | 309 | 96 | 12 | |
| III-C | 29 | 23 | 6 | 0 | |
| III-D | 179 | 145 | 31 | 5 | |
| Type V | V-A | 28 | 14 | 6 | 1 |
| V-B | 3 | 3 | 0 | 0 | |
| Type VI | VI-A | 2 | 2 | 1 | 0 |
| VI-B | 56 | 16 | 9 | 2 | |
| VI-C | 2 | 1 | 0 | 0 | |
| NA | 1996 | 1459 | 315 | 32 | |
|
| |||||
| Total | 15274 | 6533 | 1945 | 512 | |