Table 3.
Multivariable random effect logistic regression analysis assessing the association between patient, medical and facility characteristics and having a multi-drug resistant Gram-negative organism in culture (n=27,904).
| Characteristics | Adjusted OR (95% CI) |
|---|---|
| Age in years | |
| <50 | Reference |
| 50-64 | 1.40 (1.21-1.63) |
| 65+ | 1.41 (1.21-1.64) |
| Race/Ethnicity | |
| White | Reference |
| Black | 1.58 (1.39-1.78) |
| Hispanic | 1.58 (1.28-1.95) |
| Other/Missing | 1.21 (1.00-1.46) |
| Complete Injury (vs incomplete/missing) | 1.40 (1.26-1.57) |
| Duration of injury in year | |
| <=10 years (missing) | Reference |
| 11-20 | 0.87 (0.76-1.00) |
| 21+ | 0.85 (0.75-0.95) |
| U.S. region | |
| South | Reference |
| Northeast | 1.04 (0.87-1.23) |
| Midwest | 0.60 (0.53-0.69) |
| West | 0.78 (0.68-0.89) |
| Care Setting | |
| Outpatient | Reference |
| Inpatient | 1.18 (1.08-1.29) |
| Long-term care | 1.36 (1.11-1.66) |
| Home care | 1.23 (0.97-1.57) |
| Specimen type | |
| Urine | Reference |
| Blood | 0.75 (0.59-0.94) |
| Other | 0.71 (0.64-0.79) |
| Polymicrobial culture | 2.67 (2.46-2.90) |
| Mean Charlson score | 1.05 (1.03-1.08) |
| Any healthcare in past 90 days | 1.21 (1.12-1.32) |
| Any antibiotics in past 90 days | 1.62 (1.50-1.76) |
| Model with individual antibiotics included | |
| Fluoroquinolones | 1.97 (1.82-2.13) |
| Sulfonamides | 1.48 (1.34-1.63) |
| Carbapenems | 1.35 (1.18-1.53) |
| Extended spectrum penicillins* | 1.22 (1.10-3.37) |
| Tetracyclines | 1.37 (1.19-1.58) |
*
Includes piperacillin, piperacillin/tazobactam, and ticarcillin/clavulanate