Table 2. Properties of Blank/DOX-Loaded Copolymer Micelles.
diameter
(nm) |
|||||||
---|---|---|---|---|---|---|---|
CMC (mg/L) | by DLSa | by TEMb | PDI by DLSc | DLC (wt %)d | EE (wt %)d | Fc (mg/g)e | |
Polymer-1 | 2.3 | 143.9/120.5 | 43.5/24.8 | 0.135/0.210 | 6.1 | 67.1 | |
Polymer-2 | 2.5 | 169.7/134.7 | 55.7/44.4 | 0.124/0.188 | 6.8 | 74.8 | 7.8 |
Polymer-3 | 2.4 | 145.8/110.8 | 46.9/34.5 | 0.141/0.301 | 7.1 | 78.1 | |
Polymer-4 | 2.8 | 159.9/130.0 | 48.6/34.5 | 0.117/0.258 | 8.0 | 88.2 | 8.2 |
Hydrodynamic diameter of blank micelles/DOX-loaded micelles in water.
Estimated by TEM.
Polvdispersity index of blank micelles/DOX-loaded micelles obtained from DLS measurements.
Measured by a UV spectrophotometer at 482 nm.
Measured by a UV spectrophotometer at 447 nm.