Table II.

Results of regression analyses on gene expression vs. cumulative alcohol drinking

Brain region	Sex	Treatment	Gene	R-squared values	p-values
mPFC	Males	Control	Tlr4	0.083	0.58
			Il1b	0.217	0.35
			Il33	0.104	0.53
			Mbp	0.206	0.37
		Alcohol	Tlr4	0.015	0.82
			Il1b	0.123	0.50
			Il33	0.013	0.83
			Mbp	0.098	0.55
	Females	Control	Tlr4	0.030	0.74
			Il1b	0.258	0.30
			Il33	0.039	0.75
			Mbp	0.037	0.72
		Alcohol	Tlr4* (−)	0.764	0.02 *
			Il1b	0.090	0.62
			Il33	0.037	0.71
			Mbp	0.005	0.90
Hippocampus	Male	Control	Tlr4	0.123	0.50
			Il1b	0.039	0.71
			Il33	0.075	0.66
			Mbp	0.103	0.53
		Alcohol	Tlr4	0.059	0.64
			Il1b* (+)	0.878	0.02 *
			Il33	0.106	0.53
			Mbp	0.001	0.97
	Female	Control	Tlr4	0.020	0.82
			Il1b	0.209	0.36
			Il33	0.414	0.24
			Mbp	0.222	0.35
		Alcohol	Tlr4	0.121	0.50
			Il1b	0.026	0.76
			Il33	0.401	0.25
			Mbp	0.188	0.39