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Genotypes and antibiotic susceptibilities of selected H37Rv pyridomycin- and OH190-resistant isolates
| Isolate | Genotypea | MIC (μg/ml) |
||
|---|---|---|---|---|
| Pyridomycin | OH190 | Isoniazid | ||
| Parental H37Rv | WT | 0.8 | 1.6 | 0.08 |
| PYR RC10.1 | InhA(M161L) | 25 | 12.5 | 0.08 |
| PYR RC10.2 | InhA(M161L) | 12.5 | 6.3 | 0.04 |
| PYR RC20.1 | InhA(M161L) | 25 | 12.5 | 0.04 |
| OH190 RC10.4 | Rv0678(A71D) | 1.6 | 3.1 | 0.08 |
| OH190 RC10.5 | Rv0678::IS6110 | 1.6 | 3.1 | 0.08 |
| OH190 RC20.1 | Rv0678(N70D) | 1.6 | 3.1 | 0.08 |
WT, wild type.
