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A schematic illustrating the suppression of cell proliferation and increased CD8+ T cell response upon treatment of ESCC tumours with indomethacin. Indomethacin directly binds to ITGAV, promotes the SYVN1‐mediated degradation of ITGAV and modulates the downstream FAK/PI3K/AKT and TGFβ/SMAD2/3 signalling pathways
