Table 1.
Weight parameters, blood and liver biomarkers.
| Groups | Control | Periodontitis |
|---|---|---|
| Weight parameters | ||
| Body (g) | 218.4 ± 5.0 | 226.5 ± 4.6 |
| Liver | ||
| Relative (%) | 3.2 ± 0.1 | 3.0 ± 0.1 |
| Absolute (g) | 7.1 ± 0.3 | 7.0 ± 0.4 |
| Blood biomarkers | ||
| AlkP (U/dL) | 46.1 ± 6.9 | 67.9 ± 5.7* |
| AST (U/dL) | 67.2 ± 2.3 | 87.6 ± 6.1 |
| ALT (U/dL) | 28.5 ± 2.5 | 34.9 ± 1.7 |
| GGT (U/dL) | 10.1 ± 2.5 | 15.4 ± 3.8 |
| Glucose# (mg/dL) | 268.1 ± 14.5 | 259.6 ± 18.6 |
| Total cholesterol (mg/dL) | 62.4 ± 2.2 | 80.3 ± 4.9* |
| HDL (mg/dL) | 77.4 ± 3.0 | 38.2 ± 1.4* |
| Triglycerides (mg/dL) | 58.1 ± 3.8 | 84.7 ± 3.6* |
| Liver biomarkers | ||
| Total cholesterol (mg/dL) | 2.4 ± 0.4 | 5.2 ± 1.0* |
| Triglycerides | 97.2 ± 5.0 | 134.3 ± 11.8* |
| IL-1β (pg/mg) | 307.5 ± 7.6 | 302.7 ± 13.1 |
| TNF-α (pg/mg) | 239.4 ± 4.1 | 247.4 ± 3.7 |
| NO3/NO2 (mM) | 0.2 ± 0.0 | 0.3 ± 0.0* |
| MDA (mmol/g of the tissue) | 84.0 ± 3.7 | 122.0 ± 9.7* |
| GSH (μmol/g of the tissue) | 461.7 ± 37.9 | 150.0 ± 45.3* |
| MPO (mmol/g of the tissue) | 3.2 ± 0.2 | 3.7 ± 0.3 |
*
p < 0.05 comparing to periodontitis versus control groups (unpaired T-test).
Results were expressed as mean ± S.E.M.
#
Random Blood Glucose.