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. 2021 Aug 11;9(1):10.1128/spectrum.00315-21. doi: 10.1128/spectrum.00315-21

TABLE 3.

Summary of discrepancies between the VOC assays and genome sequencing

Discrepancy Issue No. of samples Lineage by genome sequencing
Misclassified as P.1/B.1.351 Presence of C21774T mutation adjacent to H68/V70 deletion region 8 B.1.1.7
Presence of N501Y mutation but absence of other VOC-specific mutations 27 B.1
2 B.1.438
Misclassified as wild-type N501Y mutation undetected by the variant assay 2 B.1.1.7