TABLE 2.
Introduction of furin cleavage site affecting changes in the virus population following virus propagation in Vero E6 cells
| Percentage of the sequencing reads having this change |
||||
|---|---|---|---|---|
| Isolate | Sample | 23,583–23,597 deletion (S gene) | 23,606 C → T (aa R682W) (S gene) | Percentage of wild-type populationa |
| hCoV-19/Finland/1/2020 | Fin-1 swab sample | 0% | 0% | 100% |
| Fin-1 VE6 p3 | 78% | 3% | 19–22% | |
| hCoV-19/Fin-25/2020 | Fin-25 swab sample | 0% | 0% | 100% |
| Fin-25 VE6 p3 | 38% | 32% | 30–62% | |
| hCoV-19/Finland/3/2020 | Fin-3 swab sample | 0% | 0% | 100% |
| Fin-3 VE6 p2 | 33% | 14% | 53–67% | |
| hCoV-19/Finland/4/2020 | Fin-4 swab sample | 0% | 0% | 100% |
| Fin-4 VE6 p2 | 7% | 42% | 51–58% | |
a
The percentages vary since the sequence analysis does not specify whether either one or both mutations reside in the same virus particle.