Table 2.

List of compounds tested against SARS-CoV-2 and their chemical structures.^a

Name of the compound	Chemical structure	Function	Reference
Camostat mesylate		Protease inhibitor	[137]
PB28		Replication of SARS-CoV-2 by inhibiting the translation of viral RNA, or by modulation cell signaling	[232], [233]
Zotatifin		Replication of SARS-CoV-2 by inhibiting the translation of viral RNA, or by modulation cell signaling	[232], [233]
Cloperastine		Antihistamines showed good antiviral properties	[233]
Clemastine		Antihistamines showed good antiviral properties	[233]
Famotidine (Pepcid)		Targets histamine H2 receptors which are abundant in all parts of the body release of histamine by the mast cells is blocked and the overreaction of immune system dampened	[234] [235]
Remdesivir		Inhibitors of viral RdRp's
EIDD-2801 (Molnupiravir)		Inhibitors of viral RdRps	[219], [220], [221]
Favipiravir		Inhibitors of viral RdRp's	[219], [220], [221]
Tautomers of EIDD-1931		Antiviral against RNA viruses	[189]
Dexamethasone		Suppresses the overreaction of the immune system	[236]
Hydroxychloroquine		Anti-malarial drug. Inhibits viral replication in vitro Now not recommended for COVID-19 treatment	[237], [238], [239], [240]
Baricitinib		Anti-inflammation rheumatoid arthritis drug Could prevent the cytokine storm	[241], [242], [243]
Ruxolittinib		A cancer drug Could prevent the cytokine storm	[241], [242], [243]
Brensocatib			[231]
Abu-Bip-CN			[231]
IcatCxpz41			[231]

^aStructures created with ChemDraw.