Fig. 4. Effect of ilaprazole on interleukin (IL)-1β in terminal ileus of each group.

Anti-inflammation effect of the ilaprazole at the terminal ileus of the postoperative ileus (POI)-induced rats. IL-1β concentration was detected absorbance in 450 nm (n = 6). Control: not open the abdomen treated with 4 ml/kg 0.5 % CMC-Na; vehicle: POI rats treated with 4 ml/kg 0.5 % CMC-Na; ilaprazole 1 mg/kg: POI rats treated with ilaprazole 1 mg/kg; ilaprazole 3 mg/kg: POI rats treated with ilaprazole 3 mg/kg; ilaprazole 10 mg/kg: POI rats treated with ilaprazole 10 mg/kg; The data was expressed as means ± SEM. Dunnett’s test was performed post-hoc for the ANOVA. ***p < 0.001 vs. control group, ^##p < 0.01, ^###p < 0.001 vs. vehicle group.