Table 3.

The diurnal relative abundance of gut microbiota at the family level in young and aged mice

Family	Young			Aged		p-value
	AM	PM		AM	PM
Male
Rikenellaceae	14.20 ± 6.35	21.57 ± 5.64		3.60 ± 0.86	3.93 ± 0.45	0.11
Muribaculaceae	11.37 ± 3.50	19.47 ± 2.86		24.83 ± 2.28	17.00 ± 4.54	0.12
Prevotellaceae	2.50 ± 2.11	15.07 ± 1.30		8.17 ± 2.86	3.77 ± 2.13	0.06
Bacteroidaceae	0.40 ± 0.12	1.97 ± 0.37		3.53 ± 0.95	3.07 ± 0.95	0.05
Lachnospiraceae	18.87 ± 4.78	11.30 ± 3.38		38.58 ± 4.10	48.45 ± 6.13	0.08
Ruminococcaceae	5.69 ± 1.62	9.20 ± 0.99		6.17 ± 1.64	7.04 ± 2.01	0.61
Clostridiales vadin BB60 group	5.22 ± 2.01	6.72 ± 0.79		3.50 ± 1.42	1.27 ± 0.29	0.24
Helicobacteraceae	39.16 ± 8.22	12.13 ± 3.28		6.29 ± 1.87	8.97 ± 2.99	0.08
Saccharimonadaceae	1.24 ± 1.13	0.32 ± 0.06		0.50 ± 0.04	0.05 ± 0.05	0.06
Deferribacteraceae	0.01 ± 0.01	0.01 ± 0.01		0.11 ± 0.09	3.08 ± 1.91	0.23
Female
Rikenellaceae	10.63 ± 6.78	11.16 ± 1.91		20.85 ± 3.48	18.94 ± 1.95	0.24
Muribaculaceae	35.37 ± 2.84	22.29 ± 1.88		14.78 ± 4.71	19.19 ± 5.43	0.08
Prevotellaceae	1.61 ± 0.06	0.64 ± 0.33		3.89 ± 1.12	3.94 ± 1.72	0.05
Bacteroidaceae	4.47 ± 0.26	3.36 ± 2.39		5.43 ± 1.11	4.90 ± 0.88	0.86
Lachnospiraceae	19.10 ± 3.56	28.76 ± 4.39		41.38 ± 7.42	27.34 ± 2.48	0.05
Ruminococcaceae	9.85 ± 1.67	8.18 ± 0.56		4.70 ± 0.37	7.37 ± 0.72	0.06
Clostridiales vadin BB60 group	8.34 ± 1.14	11.90 ± 2.03		5.40 ± 1.081	6.90 ± 0.66	0.09
Peptostreptococcaceae	0	0.43 ± 0.15		0.01 ± 0.01	1.13 ± 0.49	0.15
Helicobacteraceae	9.36 ± 2.53	11.47 ± 0.68		2.50 ± 1.24	6.37 ± 3.47	0.13
Sutterellaceae	0	0		0	1.30 ± 0.51	0.04

Values are presented as mean ± SEM. Families listed at > 1% relative abundance.