Table 2.

Change of AIS grade by time-to-enrollment groups

Study	Total No. of patients	AIS grade change	Percent age of change	Group 1			Group 2			Group 3
				No. of patients	AIS grade change	Percentage of change	No. of patients	AIS grade change	Percentage of change	No. of patients	AIS grade change	Percentage of change
Grijalva et al., 2010	14	1	7							14	1	7
Lima et al., 2010	20	6	30				3	0	0	17	8	47
Rao et al., 2013	8	8	100	5	5	100%	3	3	100
Chen et al., 2014	5	0	0							5	0	0
El-Kheir et al., 2014	50	17	34				41	15	37	9	2	22
Mendonca et al., 2014	14	8	57				2	0	0	12	8	67
Shin et al., 2015	19	5	16	19	5	26%
Hur et al., 2016	14	2	14	6	0	0%	6	2	33	2	0	0
Vaquero et al., 2016	12	4	33							12	4	33