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. 2021 Sep 17;17(5):1138–1145. doi: 10.4103/1673-5374.324854

Figure 4.

Figure 4

Ang-(1–7) attenuates apoptosis in the rotenone-induced cell model in a MasR-dependent manner.

(A) The cleaved caspase-3 levels of four groups were determined by Western blot assay. (B) Quantitative results of cleaved caspase-3 expression. (C) Caspase-3 activity was determined by colorimetric assay. Data are expressed as the mean ± SD (B, C: n = 3, one-way analysis of variance followed by Tukey's post hoc test). *P < 0.05, **P < 0.01, vs. ROT + Ang-(1–7) group; ###P < 0.001, vs. control group; ††P < 0.01, vs. ROT group. Ang-(1–7): Angiotensin-(1–7); MasR: Mas receptor; ROT: rotenone.