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. 2021 Oct 28;17(11):e10396. doi: 10.15252/msb.202110396

Figure 3. Bait–bait correlation analysis reveals molecular function clusters.

Figure 3

The correlation analysis (Pearson correlation coefficient) of bait–bait interaction profiles was performed based on average spectral counts (AvgSpec) (Liu et al, 2010) and visualized via a hierarchical clustering heatmap. Direct PPIs connecting bait proteins that form clusters on the heatmap are highlighted for several clusters.
  • A
    Viral bait–bait correlation.
  • B
    The overlap of proteins in each cluster is shown in a Venn diagram.
  • C
    A bar diagram of the enriched pathways associated with the clusters shown and ranked by P‐value.
  • D
    Host–receptor bait–bait correlation; the N‐ and C‐terminal tags on the same bait are indicated.
  • E
    The bar chart represents the association of cluster 1 with specific pathways.