FGFR1 signaling is required for the normal cell cycle progression of human mesenchymal stem cells (hMSCs). Changes in FGFR1 expression and cell number following receptor inhibition by siRNA knockdown, neutralizing antibody challenge, or drug inhibition over 6 days. Abbreviations: FGFR1, fibroblast growth factor receptor 1; REU, relative expression unit; siRNA, small interfering RNA.