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. Author manuscript; available in PMC: 2021 Oct 28.
Published in final edited form as: Stem Cells. 2013 Dec;31(12):2724–2736. doi: 10.1002/stem.1514

Figure 2.

Figure 2.

Mediators of human mesenchymal stem cell (hMSC) proliferation. (A): hMSC growth over 6 days after inhibition of known FGFR signal transducers. (B): Cell cycle progression in hMSCs under FGFR1 inhibition. (C): Analysis of cell division after 48 hours using CFDA fluorescence. (D): Recovery of hMSC growth following FGFR1 inhibition after 6 days. (E, F): The effect of FGFR1 inhibition on Histone H4 (E) and Cyclin B2 (F) mRNA expression. Abbreviations: DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; FBS, fetal bovine serum; FGFR1, fibroblast growth factor receptor 1; PI3K, phosphatidylinositide 3-kinases; PKC, protein kinase C.