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. Author manuscript; available in PMC: 2021 Oct 28.
Published in final edited form as: Stem Cells. 2013 Dec;31(12):2724–2736. doi: 10.1002/stem.1514

Figure 4.

Figure 4.

Fibroblast growth factor receptor 1 (FGFR1) signaling regulates the expression of p21 and p27 through c-Myc (A): Polymerase chain reaction (PCR) analysis of c-Myc expression upon reentry into the cell cycle in the presence of the FGFR1 inhibitor. (B): Expression of p21 and p27 calculated as a ratio of treatment with SU5402 as compared to vehicle in human mesenchymal stem cells (hMSCs) overexpressing c-Myc. (C): The effect of SU5402 on the p21 promoter in c-Myc-overexpressing hMSCs over a 48-hour period. The asterisk (*) was to indicate that there was significant difference between the two groups. Abbreviations: REU, relative expression unit; RLU, relative light unit.