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. Author manuscript; available in PMC: 2022 Jan 8.
Published in final edited form as: Nat Aging. 2021 Jul 8;1(7):585–597. doi: 10.1038/s43587-021-00072-0

Extended Data Fig. 2 |. Sustained and severity-dependent activation of AP1.

Extended Data Fig. 2 |

a, Representative z-stacked whole mount brains at 1 dpi in flies with dsRed expressed under a mutated TRE-promoter (MREdsRed; representative of n = 9 – 11 brains per condition from two independent experiments). b, Mean relative expression of select RNAseq predicted AP1 genes by RT-qPCR at 1, 7 and 15 dpi across injury conditions (each point = 1 biological replicate, 9 dissected brains; n = 6 biological replicates per condition; Kruskal–Wallis test with Dunn’s multiple comparison test and Holm adjustment for each gene). Black symbols, sham. Pink symbols, mild dTBI. Red symbols, severe dTBI. Statistical annotations are ****p<0.0001, ***p<0.001, **p<0.01, *p<0.05, .<p<0.10. All scale bars 100 μm. See Supplementary Table 1 for genotypes.