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. Author manuscript; available in PMC: 2022 Jan 8.
Published in final edited form as: Nat Aging. 2021 Jul 8;1(7):585–597. doi: 10.1038/s43587-021-00072-0

Fig. 8 |. AP1 activity decades after moderate TBI in humans.

Fig. 8 |

a, The 12 enriched motifs detected by HOMER among upregulated genes in TBI donors (FDR<0.05), colored by enrichment relative to non-TBI donors. b, Violin plots showing expression of select predicted FRA1/JUND genes in non-TBI (black; n = 81 samples) and TBI (red; n = 80 samples) donors (FDR<0.10). See Extended Data Fig. 8d for all target genes. c, Pearson correlation between JUNB expression and % area GFAP+ versus Iba1+ by IHC in non-TBI (black; n = 81 samples) and TBI (red; n = 80 samples) donors (each point = 1 sample; 95% confidence interval shown; without adjustment for multiple comparison). d, Pearson correlation between JUNB expression and % area AT8+ by IHC in non-TBI (black; n = 81 samples) and TBI (red; n = 80 samples) donors (each point = 1 sample; 95% confidence interval shown).