Table 2. List of isolated or biochemically tested components (enzymes or inhibitors) from the venoms of Latrodectus spp.

Molecules	Species
α-LTXs	L. m. tredecimguttatus/L. tredecimguttatus: α-LTX-Lt1a [176]
	L. mactans: α-LTX-Lm1a [188]
	L. hesperus: α-LTX-Lhe1a [188]
	L. hasselti: α-LTX-Lh1a [188]
LITs	L. m. tredecimguttatus/L. tredecimguttatus: α-LIT-Lt1a [177],
	δ-LIT-Lt1a [174], ß-LIT, γ-LIT, and ε-LIT [148]
	L. hasselti: α-LIT-Lh1a and δ-LIT-Lh1a [188]
	L. hesperus: δ-LIT-Lhe1a [188]
α-LCT	L. m. tredecimguttatus/L. tredecimguttatus: α-LCT-Lt1a [148]
Latrodectins	L. m. tredecimguttatus/L. tredecimguttatus [182, 183]
	L. geometricus [185]
	L. hesperus [185]
Peptide inhibitor of angiotensin-converting enzyme	L. tredecimguttatus [147]
Hyaluronidase	L. tredecimguttatus [113]
	L. mactans [113]
Collagenase	L. geometricus [134]
Phosphodiesterase	L. mactans (from North America*) [189]
Bradykinin-inactivating enzyme (kininase)-thiol endopeptidase	L. tredecimguttatus [190]**
Serotonin	L. tredecimguttatus [191]
Free amino acids (glutamic acid, aspartic acid, GABA, and taurine)	L. tredecimguttatus [3, 147]
Purine derivatives (adenosine, guanosine, inosine, and 2,4,6-trihydroxypurine)	L. menavodi [192]

^*Considering the great distribution and the taxonomic uncertainty of the species, the authors prefer to identify the origin of the venom when present in the original work.

^**The authors reported that L. tredecimguttatus has no proteolytic activity against casein and hemoglobin. Moreover, Frontali et al. [150] did not detect lipolytic or proteolytic action of a toxic fraction of Latrodectus venom against Azocoll.