Fig 8. Impact of the choice of prior on the posterior distribution for ℓ_Cinf.

A: Non-normalized priors for log₁₀(specific infections, SIN/mL) = ℓ_Cinf that are uniform in either C_inf or ℓ_Cinf are shown. A prior uniform in C_inf is biased towards larger values of ℓ_Cinf. B: Updated posterior belief about ℓ_Cinf for each of the two prior beliefs shown in A, as per Eqs (7) and (8), after having observed the ED assay example provided in Fig 1. While the prior uniform in C_inf yields a posterior with a mode of ℓ_Cinf = 6.21, that for a prior uniform in ℓ_Cinf yields a mode of ℓ_Cinf = 6.18.