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. 2021 Oct 28;16(10):e0258841. doi: 10.1371/journal.pone.0258841

Table 1. Descriptive data of included patients according to heart-rate-variability (HRV).

Variables SDNN ≤ 8 SDNN > 8 p RMSSD ≤ 8 RMSSD > 8 p
N 142 129 147 124
Age, years* 68 [59–75] 71 [60–79] 0.106 66 [57–73] 72 [62–81] <0.001
Sex, n (%) 0.874 0.508
    Women 57 (40.1) 53 (41.1) 57 (38.8) 53 (42.7)
    Men 85 (59.9) 76 (58.9) 90 (61.2) 71 (57.3)
Comorbidities, n (%)
    Chronic heart disease 37 (27.6) 36 (30.3) 0.644 28 (20.0) 45 (39.8) 0.001
    Hypertension 70 (51.1) 62 (49.6) 0.809 63 (44.4) 69 (55.6) 0.034
    Obesity 50 (37.0) 34 (27.6) 0.108 53 (37.6) 31 (26.5) 0.058
    Diabetes 21 (16.9) 20 (17.7) 0.877 24 (17.9) 17 (16.5) 0.777

* Non normal-distributed data presented as median with interquartile range.

Note: SDNN = standard deviation of normal to normal heartbeat intervals; RMSSD = root mean square of successive differences between adjacent heartbeats. Both SDNN and RMSSD cut-offs are in msec.