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. 2021 Oct 14;12:724759. doi: 10.3389/fpsyt.2021.724759

Table 2.

Fixed effects of time and group in a Linear Mixed model, with follow-up over 10 years in ASD, ADHD, and TD groups.

ASEBA scale Internalizing Externalizing Total problems
Estimate SE 95% CI Estimate SE 95% CI Estimate SE 95% CI
Main effect of group
TD 0 (ref) 0 (ref) 0 (ref)
ADHD 16.92*** 1.80 13.37, 20.48 19.02*** 1.75 15.57, 22.46 24.02*** 1.56 20.96, 27.07
ASD 23.18*** 2.17 18.90, 27.46 18.25*** 2.10 14.10, 22.40 26.23*** 1.87 22.55, 29.91
ADHD (ref) vs. ASD 6.26** 2.06 2.17, 10.34 −0.77 2.05 −4.83, 3.29 2.21 1.69 −1.12, 5.55
Main effect of time
T1–T2 −1.25 1.33 −3.88, 1.38 −1.09 1.23 −3.52, 1.34 −1.32 1.23 −3.74, 1.10
T2–T3 4.85* 2.18 0.54, 9.16 3.62 1.98 −0.29, 7.53 7.47*** 2.15 3.21, 11.72
Interaction group × time (T1–T2)
TD 0 (ref) 0 (ref) 0 (ref)
ADHD −1.49 1.69 −4.82, 1.85 −3.52* 1.56 −6.59, −0.45 −2.72 1.56 −5.80, 0.35
ASD −4.38* 2.07 −8.47, −0.29 −7.97*** 1.90 −11.73, −4.21 −6.32*** 1.91 −10.09, −2.54
ADHD (ref) vs. ASD −2.89 1.98 −6.82, 1.04 −4.45* 1.89 −8.19, −0.72 −3.58* 1.79 −7.12, −0.05
Interaction group × time (T2–T3)
TD 0 (ref) 0 (ref) 0 (ref)
ADHD −7.65** 2.81 −13.21, −2.09 −7.45** 2.55 −12.49, −2.41 −10.77*** 2.15 −16.26, −5.28
ASD −8.19* 3.54 −15.19, −1.20 −3.91 3.21 −10.23, 2.42 −9.55** 3.49 −16.44, −2.65
ADHD (ref.) vs. ASD −0.38 3.71 −7.74, 6.98 3.62 3.34 −3.00, 10.24 1.30 3.41 −5.45, 8.05

Internalizing, externalizing, and total problems = Achenbach System of Empirically Based Assessment; ADHD, attention-deficit/hyperactivity disorder; ASD, autism spectrum disorder; TD, typically developing; T1, baseline; T2, 2-year follow-up; T3, 10-year follow-up.

*

p < 0.05,

**

p < 0.01,

***

p < 0.001.