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. 2021 Oct 29;31:100989. doi: 10.1016/j.mgene.2021.100989

Table 1.

Allele and genotype distribution of six SNPs in IL37 gene among COVID-19 patients and controls.

SNP Allele/Genotype Patients (N = 100)
Controls (N = 100)
OR 95% CI p-value (pc)
N % N %
rs3811042 A 72 36.0 79 39.5 Reference
G 128 64.0 121 60.5 1.16 0.78–1.74 0.536 (1.0)
AA 20 20.0 19 19.0 Reference
AG 32 32.0 41 41.0 0.68 0.38–1.20 0.240 (1.0)
GG 48 48.0 40 40.0 1.38 0.79–2.42 0.319 (1.0)
HWE-p 0.155
rs3811043 C 80 40.0 64 32.0 Reference
G 120 60.0 136 68.0 0.71 0.47–1.06 0.118 (0.59)
CC 13 13.0 9 9.0 Reference
CG 54 54.0 46 46.0 1.38 0.79–2.40 0.322 (1.0)
GG 33 33.0 45 45.0 0.60 0.34–1.07 0.111 (0.555)
HWE-p 0.568
rs2466449 A 186 93.0 183 91.5 Reference
G 14 7.0 17 8.5 0.81 0.39–1.69 0.709 (1.0)
AA 86 86.0 83 83.0 Reference
AG 14 14.0 17 17.0 0.79 0.37–1.71 0.696 (1.0)
HWE-p 0.352
rs3811045 C 132 66.0 143 71.5 Reference
T 68 34.0 57 28.5 1.29 0.85–1.97 0.281 (1.0)
CC 45 45.0 53 53.0 Reference
CT 42 42.0 37 37.0 1.23 0.70–2.17 0.563 (1.0)
TT 13 130 10 10.0 1.34 0.56–3.21 0.658 (1.0)
HWE-p 0.356
rs3811046 T 125 62.5 138 69.0 Reference
G 75 37.5 62 31.0 1.34 0.88–2.02 0.206 (1.0)
TT 32 32.0 50 50.0 Reference
TG 61 61.0 38 38.0 2.55 1.45–4.50 0.002 (0.01)
GG 7 7.0 12 12.0 0.55 0.21–1.46 0.335 (1.0)
HWE-p 0.263
rs3811047 G 155 77.5 170 85.0 Reference
A 45 22.5 30 15.0 1.65 0.99–2.74 0.072 (0.36)
GG 58 58.0 73 73.0 Reference
GA 39 39.0 24 24.0 2.02 1.10–3.71 0.033 (0.165)
AA 3 3.0 3 3.0 1.00 0.20–5.04 1.0 (1.0)
HWE-p 0.556

SNP: Single nucleotide polymorphism; HWE-p: Hardy-Weinberg probability; N: Absolute number; OR: Odds ratio; CI: Confidence interval; p: Two-tailed Fisher's exact probability; pc: Bonferroni correction probability. Significant p-value is bold-marked.