Table 1.

Clinical diagnostic criteria for neurofibromatosis type I.

Diagnostic criteria of NF1

Two of the following signs

Six colored spots or more, measuring at least 5 mm before puberty and 15 mm after puberty

Lentigines in the axillary or inguinal region

Optic nerve glioma

Two neurofibromas of any type or plexiform fibroid

Two or more s

Bone abnormalities such as a dysplastic sphenoid bone or very fine long bone cortex

First-degree relative suffering from this disease