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. 2021 Nov 1;131(21):e150613. doi: 10.1172/JCI150613

Figure 5. OC43-SECTO–reactive clones show limited yet antigenically evolving cross-reactivity with SARS-CoV-2.

Figure 5

All OC43-SECTO–reactive clones (n = 920) from 17 patients with severe COVID-19 were stratified by week number after the onset of clinical symptoms. The proportion of single OC43-SECTO (blue) and SARS-CoV-2 cross-reactive clones (gray) is shown (left pie). The cross-reactivity with 1 (green colors), 2 (yellow and orange colors), and 3 SARS-CoV-2 antigens (red) is depicted (right pie). The number of patients analyzed per week is indicated on the left. The frequency and number of contributing clones for each cluster are shown inside and adjacent to each part, respectively.